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Suggest Treatment For Allergic Reaction To Paraphenylenediamine

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Posted on Wed, 12 Oct 2016
Question: I have a PPD allergy. Is the medication chlorthalidone related?
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Answered by Dr. Ronald Schubert (21 minutes later)
Brief Answer:
PPD allergy and chlorthalidone

Detailed Answer:
Thank you for contacting HCM with your health care concerns

You have an allergy to PPD and you are concerned that chlorthalidone may also react because of your PPD allergy. The answer is no. They are tow completely different agents. But you do mention that you were on HCTZ and developed heart palpitations and muscle cramping. Chlorthalidone is of the same family as HCTZ and you can develop the same side effects. So I would caution you on taking chlorthalidone if you had prior problems with HCTZ.

I hope I answered your question. Please contact us again if you have any additional questions.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Follow up: Dr. Ronald Schubert (32 minutes later)
Is there another medication not related to HCTZ that would be effective?
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Answered by Dr. Ronald Schubert (4 minutes later)
Brief Answer:
Hypertension

Detailed Answer:
If your doctor is considering using the chlorthalidone for blood pressure control there are several other choices. You just not able to use thiazide diuretics. They can use furosemide which is a loop diuretic, there are potassium sparing diuretics like triamterene and androgen receptor blocker like spitonolactone.
Note: For further queries related to coronary artery disease and prevention, click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Ronald Schubert

General & Family Physician

Practicing since :1984

Answered : 2407 Questions

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Suggest Treatment For Allergic Reaction To Paraphenylenediamine

Brief Answer: PPD allergy and chlorthalidone Detailed Answer: Thank you for contacting HCM with your health care concerns You have an allergy to PPD and you are concerned that chlorthalidone may also react because of your PPD allergy. The answer is no. They are tow completely different agents. But you do mention that you were on HCTZ and developed heart palpitations and muscle cramping. Chlorthalidone is of the same family as HCTZ and you can develop the same side effects. So I would caution you on taking chlorthalidone if you had prior problems with HCTZ. I hope I answered your question. Please contact us again if you have any additional questions.