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What Causes Elevated LDH Levels?
Question: Dear sir before I had send my blood test report to healthcaremagic, which was the LDH level high, HCM advise me to isoenzyme test then I advise from Dr XXXXXXX XXXXXXX , He advise me this level is normal but sir in the blood test report LDH level is high so I want to test it further isoenzyme test, I approach in the lab but isoenzyme test not there, please tell me the full and detail name of this isoenzyme test or what should consult a doctor
Brief Answer:
I would explain as follows:
Detailed Answer:
Hello!
Thank you for asking on HCM!
I carefully reviewed your uploaded tests and would explain that except for LDH levels, your complete blood count, sedimentation rate, plasma glucose, renal function tests and Zinc plasma levels are quite normal.
The lactate dehydrogenase (LDH) isoenzyme test checks how much of the different types of LDH are in the blood.
This test is usually done when your doctor thinks you might have high LDH levels. Measurement of LDH isoenzymes helps determine the location of any tissue damage.
LDH is found in many body tissues such as the heart, liver, kidney, skeletal muscle, brain, blood cells, and lungs.
LDH exists in five forms, which differ slightly in structure.
LDH-1 is found primarily in heart muscle and red blood cells.
LDH-2 is concentrated in white blood cells.
LDH-3 is highest in the lung.
LDH-4 is highest in the kidney, placenta, and pancreas.
LDH-5 is highest in the liver and skeletal muscle.
All of these can be measured in the blood. The test is called Lactic (lactate) dehydrogenase isoenzymes.
But, based on your tests, I would explain as follows:
1- Your complete blood count is quite normal. So anemia and any other blood disorders have been excluded as a possible cause of LDH increased levels.
2- Your liver function tests are normal. So kidney disorders have been excluded too.
3- Your sedimentation rate are normal. So inflammation has been excluded.
Coming to this point, I would recommend performing other tests to determine the possible cause of LDH increase:
- liver function tests ( AST, ALT, ALP, gama GT)
- Calcium and potassium plasma levels to examine your bone activity
- a chest X ray study.
- an abdominal ultrasound.
Other tests may be needed based on your symptomatology.
Hope you will find this answer helpful!
Kind regards,
Dr. Iliri
I would explain as follows:
Detailed Answer:
Hello!
Thank you for asking on HCM!
I carefully reviewed your uploaded tests and would explain that except for LDH levels, your complete blood count, sedimentation rate, plasma glucose, renal function tests and Zinc plasma levels are quite normal.
The lactate dehydrogenase (LDH) isoenzyme test checks how much of the different types of LDH are in the blood.
This test is usually done when your doctor thinks you might have high LDH levels. Measurement of LDH isoenzymes helps determine the location of any tissue damage.
LDH is found in many body tissues such as the heart, liver, kidney, skeletal muscle, brain, blood cells, and lungs.
LDH exists in five forms, which differ slightly in structure.
LDH-1 is found primarily in heart muscle and red blood cells.
LDH-2 is concentrated in white blood cells.
LDH-3 is highest in the lung.
LDH-4 is highest in the kidney, placenta, and pancreas.
LDH-5 is highest in the liver and skeletal muscle.
All of these can be measured in the blood. The test is called Lactic (lactate) dehydrogenase isoenzymes.
But, based on your tests, I would explain as follows:
1- Your complete blood count is quite normal. So anemia and any other blood disorders have been excluded as a possible cause of LDH increased levels.
2- Your liver function tests are normal. So kidney disorders have been excluded too.
3- Your sedimentation rate are normal. So inflammation has been excluded.
Coming to this point, I would recommend performing other tests to determine the possible cause of LDH increase:
- liver function tests ( AST, ALT, ALP, gama GT)
- Calcium and potassium plasma levels to examine your bone activity
- a chest X ray study.
- an abdominal ultrasound.
Other tests may be needed based on your symptomatology.
Hope you will find this answer helpful!
Kind regards,
Dr. Iliri
Note: For further queries related to coronary artery disease and prevention, click here.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
Answered by
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