What Causes Elevated Thyroglobulin Antibodies While Suffering From Vitiligo?

Posted on Wed, 6 Sep 2017

Question: Hi
I am being treated for vitiligo right now and my dr did blood test and i recived them back my thyrogloubin antibodies are >1000 can you please tell me what this is ?

Answered by Dr. Mirjeta Guni (58 minutes later)

Brief Answer:
About thyroid autoimmunity;

Detailed Answer:
Hello and thank you for asking!
I have gone carefully through your concern.
High thyroglobulin antibodies are suggestive for an autoimmune disease of the thyroid gland.
As you may know, vitiligo is an autoimmune pathology and usually is associated with autoimmune processes affecting other organs, that is why in these cases thyroid and some other autoimmune diseases are checked.
Thyroglobulin antibodies, attack thyroid gland and destroy it. As a result it doesn't produce hormones any more. At this point, the thyroid hormone ( levothyroxine) should be taken orally.
Elevated TSH level is suggestive for low thyroid function.
Once the thyroid gland is destroyed, it does not retake it's function anymore.
So levothyroxine is a long-term therapy.
Hope i have answered your query
Kind regards,
Dr.Mirjeta

Above answer was peer-reviewed by : Dr. Yogesh D

Follow up: Dr. Mirjeta Guni (37 minutes later)

my tsh was 2.49 in range

Answered by Dr. Mirjeta Guni (3 hours later)

Brief Answer:
Keep monitoring TSH!

Detailed Answer:
Welcome back!
Thanks you should keep monitoring it every 6 months! It means that the normal thyroid tissue remained, compensates good the thyroid function.
Once it is over 4 mUi/ ml, treatment with levothyroxine should be started.
Kind regards,
Dr.Mirjeta

Above answer was peer-reviewed by : Dr. Kampana

Follow up: Dr. Mirjeta Guni (17 minutes later)

So am I good without meds for now ? The tsh is normal but thyrogloubin high <1000

What can I do to get that number normal ??
Once vitiliago is cleared up will my numbers be normal

Answered by Dr. Mirjeta Guni (10 hours later)

Brief Answer:
About thyroid antibodies:

Detailed Answer:
Hi again,
There is no treatment to lower antithyroglobulin antibodies.
The pathology is chronic and they will continue to be high.
For the moment there is no need to start treatment for thyroid because the thyroid function is normal.
The outcome of vitiligo ia not related to anti thyroglobulin antibodies. It may improve or get worse independently of thyroglobulin antibodies.
The thyroid function is closely related to thyroglobulin antibodies and it should be monitored every 6 months.
Hope the information will help.
kind regards,
Dr.Mirjeta

Above answer was peer-reviewed by : Dr. Raju A.T

Follow up: Dr. Mirjeta Guni (4 hours later)

My glucose is 101 why is that I did not fast during test my tsh is 2.49 and white blood count 6.1 seems all normal but glucose

Answered by Dr. Mirjeta Guni (9 hours later)

Brief Answer:
The blood glucose is normal;

Detailed Answer:
Hi again,
The normal blood glucose ranges are: - fasting 70-105, postprandial ( after eating)up to 140 mg/dl.
So it is a normal value.
Best wishes,
Dr.Mirjeta

Above answer was peer-reviewed by : Dr. Kampana

Follow up: Dr. Mirjeta Guni (25 minutes later)

What about absolute menocytes that's low 153 just so strange I am all out of wack from vitiligo witch is being treated and re pigmenting

Answered by Dr. Mirjeta Guni (7 hours later)

Brief Answer:
About vitiligo treatment:

Detailed Answer:
Hello,
There are many causes of low monocytes and the whole blood count + a detailed clinical examination is needed to give you an answer about it.
You didn't mention the treatment (cream) that you are using, usually we recommend tanning creams. It is unusual for vitiligo to get re pigmented.
Regards,
Dr.Mirjeta

Above answer was peer-reviewed by : Dr. Nagamani Ng

Follow up: Dr. Mirjeta Guni (12 hours later)

Cream is fluticasone propionate and my tsh is 2.49 and WBC is 6.1

Answered by Dr. Mirjeta Guni (8 hours later)

Brief Answer:
Continue with fluticasone:

Detailed Answer:
Hi again,
TSH and white blood cell count is XXXXXXX continue with fluticasone cream for vitiligo.
Best wishes,
Dr.Mirjeta

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Above answer was peer-reviewed by : Dr. Vaishalee Punj