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What Causes Low ALT Levels Along With High Bilirubin Levels?

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Posted on Mon, 1 Dec 2014
Question: Hi,

Owing to my sudden weight loss, I have gone for various blood tests. Lever function test was one of them. The results indicate high total bilirubin (2.02), high indirect bilirubin (1.82) and low ALT (16.00). All other values are within range. Would like to know what would this indicate, and what could be the causes for same.
doctor
Answered by Dr. Indu Kumar (52 minutes later)
Brief Answer:
It is important to rule out XXXXXXX syndrome.

Detailed Answer:
Hello XXXXXXX

Mostly low ALT level indicate normal healthy liver. However, Urinary tract infections or malnutrition may also cause low ALT level in blood.

Since only total bilirubin and indirect bilirubin are high, it is important to rule out XXXXXXX syndrome. Patients with XXXXXXX syndrome usually have only mild hyperbilirubinemia especially elevated indirect bilirubin level and there is no clinical significance. It is found in 5-10% of the population.
This condition usually doesn't require any treatment.

Get well soon.
Hope I have answered your question.
Further queries are most welcome.

Take Care
Dr.Indu XXXXXXX
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Above answer was peer-reviewed by : Dr. Ashwin Bhandari
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Answered by
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Dr. Indu Kumar

Radiologist

Practicing since :2004

Answered : 6728 Questions

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What Causes Low ALT Levels Along With High Bilirubin Levels?

Brief Answer: It is important to rule out XXXXXXX syndrome. Detailed Answer: Hello XXXXXXX Mostly low ALT level indicate normal healthy liver. However, Urinary tract infections or malnutrition may also cause low ALT level in blood. Since only total bilirubin and indirect bilirubin are high, it is important to rule out XXXXXXX syndrome. Patients with XXXXXXX syndrome usually have only mild hyperbilirubinemia especially elevated indirect bilirubin level and there is no clinical significance. It is found in 5-10% of the population. This condition usually doesn't require any treatment. Get well soon. Hope I have answered your question. Further queries are most welcome. Take Care Dr.Indu XXXXXXX