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What Causes Low WBC Count While On Obinutuzumab?

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Posted on Tue, 13 Dec 2016
Question: I have CLL mild. Started treatment last week with Obinutuzumab. My WBC went from 42,000 down to 8.5K I think this must be a error what do you think ?
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Answered by Dr. Dr. Muhammad Sareer Khalil (2 hours later)
Brief Answer:
Explained

Detailed Answer:
Hello and welcome

I appreciate your concern

Obinutuzumab is a CD20 antibody, which mediates B-cell lysis. It does decrease white cell count. However, the only way to confirm this would be to repeat the cell count.

wishing you best of health

Thanks
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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Dr. Dr. Muhammad Sareer Khalil

General & Family Physician

Practicing since :2012

Answered : 2906 Questions

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What Causes Low WBC Count While On Obinutuzumab?

Brief Answer: Explained Detailed Answer: Hello and welcome I appreciate your concern Obinutuzumab is a CD20 antibody, which mediates B-cell lysis. It does decrease white cell count. However, the only way to confirm this would be to repeat the cell count. wishing you best of health Thanks