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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Does The Lab Report Mean?

Please explain what the following lab report means: "The neoplastic lymphocytes express CD45, CD20, partial BCL-2, and focal membranous CD30, but not CD5, CD10, BCL-6, cyclin D1, or CD43. CD3 nad CD43 highlight scattered small T-lymphocytes in the background
Wed, 13 Aug 2014
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Pathologist and Microbiologist 's  Response
Hello and welcome to HCM,
The interpretation of immunophenotype is as follows:
There is presence of B cell lymphoma.
Lymphoma is malignancy arising from lymphocytes.
On the basis of immunophenotypic staining the lymphoma is probably marginal zone lymphoma.
Consult your hematologist for further management.

Thanks and take care
Dr Shailja P Wahal
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What Does The Lab Report Mean?

Hello and welcome to HCM, The interpretation of immunophenotype is as follows: There is presence of B cell lymphoma. Lymphoma is malignancy arising from lymphocytes. On the basis of immunophenotypic staining the lymphoma is probably marginal zone lymphoma. Consult your hematologist for further management. Thanks and take care Dr Shailja P Wahal