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What Does This Lab Report Indicate?

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Posted on Mon, 18 Sep 2017
Question: experiencing joint pain, fatigue. ANA test result 1:1280, speckled. SS-A test pos. at 4.8. TPO result 573 but free t4 and t3 in normal range. take levothyroxine
doctor
Answered by Dr. Prof. Kunal Saha (3 hours later)
Brief Answer:
Naproxen should help

Detailed Answer:
Thanks for asking on HealthcareMagic.

I have gone carefully through your query and understand your concerns. Your join pain could be attributed to the ANA positivity but the condition calls for further investigation. You need to get a few tests done:
* Blood for RA factor, Anti XXXXXXX Antibody, C-Reactive Protein, Anti-dsDNA, Anticentromere Antibody

Further plans can be made based on the reports. Going through the following should help:
https://www.icgp.ie/assets/9/EB9FF8A7-19B9-E185-830200BC23B0AFCE_document/ANA_43-44.pdf

As of now you may benefit from taking Tab. Aleve (naproxen) 500 mg when needed (preferably in full stomach).

Let me know if I could help further.

Regards
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Prof. Kunal Saha (24 minutes later)
I have had all of the tests you mention. only positive for SS-A. could this be lupus?
doctor
Answered by Dr. Prof. Kunal Saha (1 hour later)
Brief Answer:
Could be lupus

Detailed Answer:
Thanks for writing back. Anti-Ro/SSA and Anti-La/SSB are antibodies found mostly in people with systemic lupus (30-40%) and primary Sjogren’s syndrome. They are also commonly found in people with lupus who have tested negative for anti-nuclear antibodies. Anti-Ro and anti-La can also be found in other rheumatic diseases, such as systemic sclerosis, rheumatoid arthritis, and polymyositis, and are present in low titers in about 15% of healthy individuals. These antibodies are not highly specific for systemic lupus, but they are associated with certain conditions, including extreme sun sensitivity, a clinical subset of lupus called subacute cutaneous lupus erythematosus (SCLE), and a lupus-like syndrome associated with a genetic deficiency of a substance called complement (a system of proteins that helps mediate your body’s immune response). You therefore need to visit a rheumatologist who would be able to correlate clinically.

Regards
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Prof. Kunal Saha

General & Family Physician

Practicing since :1954

Answered : 4467 Questions

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What Does This Lab Report Indicate?

Brief Answer: Naproxen should help Detailed Answer: Thanks for asking on HealthcareMagic. I have gone carefully through your query and understand your concerns. Your join pain could be attributed to the ANA positivity but the condition calls for further investigation. You need to get a few tests done: * Blood for RA factor, Anti XXXXXXX Antibody, C-Reactive Protein, Anti-dsDNA, Anticentromere Antibody Further plans can be made based on the reports. Going through the following should help: https://www.icgp.ie/assets/9/EB9FF8A7-19B9-E185-830200BC23B0AFCE_document/ANA_43-44.pdf As of now you may benefit from taking Tab. Aleve (naproxen) 500 mg when needed (preferably in full stomach). Let me know if I could help further. Regards