Hi, Thank you so much for trusting us with your health query. I am so sorry to hear about these migraines. Vicodin is only used in pregnancy when there is clearly no other safer drug and the benefits far outmatch the risk. Though direct teratogenic effects have not be reported in humans, it cannot be ruled out also. It is a class C classified drug according to the food and drug administration. I will suggest that you talk with your doctor to propose other safer options. If there should be none, then he may consider using this as a last result. I hope you find this helpful. I wish you well. Thank you so much for using our services and please do feel free to ask for more information if need. Thanks. Dr. Ditah, MD.