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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can An Ovarian Remnant Cause Retroperitoneal Leiomyosarcoma?

in 1994 I had a complete hysterectomy. in 2007 I had a 14 lb tumor removed from an ovary remnant. 5/5/14 I had retroperitoneal leiomyosarcoma removed and am now going to start radiation. 1. how is it possible to leave an ovary remnant behind? & 2 could that have caused the cancer?
Thu, 20 Nov 2014
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Pulmonologist,  's  Response
Thanks for your question on HCM.
In my opinion the newer lesions must be due to peritoneal seeding by tumpur cells.
Yes, you are right, that remnants can be left by negligence of operating surgeon and this can cause recurrence. But chances of this os very less.
During surgery, due to handling of tumour mass, there is great risk of spillage and peritoneal seeding by tumour cells. This is unavoidable. So this can give rise to recurrence. So in modern era this is the reason for which post operative chemotherapy and radiotherapy is given. The basic principle is to kill seeded malignant cells.
So peritoneal seeding during surgical handling can be the cause for your recurrence.
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Can An Ovarian Remnant Cause Retroperitoneal Leiomyosarcoma?

Thanks for your question on HCM. In my opinion the newer lesions must be due to peritoneal seeding by tumpur cells. Yes, you are right, that remnants can be left by negligence of operating surgeon and this can cause recurrence. But chances of this os very less. During surgery, due to handling of tumour mass, there is great risk of spillage and peritoneal seeding by tumour cells. This is unavoidable. So this can give rise to recurrence. So in modern era this is the reason for which post operative chemotherapy and radiotherapy is given. The basic principle is to kill seeded malignant cells. So peritoneal seeding during surgical handling can be the cause for your recurrence.