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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can I Continue With Duphastone During 28 Weeks Of Pregnancy?

hi doctor,
I am 28weeek pregnant and i was taking tab.duphastone as adviced by doctors and she told to continue till last month,now another doctor is telling not to take duphastone actually they are prescribing during in fist trimister.so i am confused,please give the correct answer.
Thanks.
Thu, 24 Apr 2014
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General & Family Physician 's  Response
Hi and welcome to HCM

Duphaston contains dydrogesterone, a progesterone. progesterone is not approved for use during pregnancy in any advanced country such as US, UK etc. Some authorities in the past used to recommend its use in recurrent miscarriage or threatened abortion but now there is now no evidence of any benefit from such practice and recommend against the use in early pregnancy unless there is proven deficiency.

One problem with this medicine is that female baby may suffer from hirsutism (unwanted hair on face, chest etc). Therefore if at all progesterones have to be given when there is documented deficiency, it is preferable to give dydrogesterone (sold as Duphaston) which your doctor has prescribed or medroxyprogesterone (sold as Meprate).

Most of the times these tablets are prescribed only during first three months of pregnancy. I advice you to have second opinion from another doctor on this. if you have history of previous abortions and current pregnancy in under risk of miscarriage then they might continue duphaston. But please take second opinion.

Regards
Dr Santosh
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Can I Continue With Duphastone During 28 Weeks Of Pregnancy?

Hi and welcome to HCM Duphaston contains dydrogesterone, a progesterone. progesterone is not approved for use during pregnancy in any advanced country such as US, UK etc. Some authorities in the past used to recommend its use in recurrent miscarriage or threatened abortion but now there is now no evidence of any benefit from such practice and recommend against the use in early pregnancy unless there is proven deficiency. One problem with this medicine is that female baby may suffer from hirsutism (unwanted hair on face, chest etc). Therefore if at all progesterones have to be given when there is documented deficiency, it is preferable to give dydrogesterone (sold as Duphaston) which your doctor has prescribed or medroxyprogesterone (sold as Meprate). Most of the times these tablets are prescribed only during first three months of pregnancy. I advice you to have second opinion from another doctor on this. if you have history of previous abortions and current pregnancy in under risk of miscarriage then they might continue duphaston. But please take second opinion. Regards Dr Santosh