Hi, Oxyelite Pro is a weight loss supplement that contains several stimulant ingredients, such as caffeine and yohimbine, which can increase heart rate and blood pressure. It is generally recommended to discontinue the use of such supplements before surgery or medical procedures due to potential risks of increased bleeding, cardiovascular events, and other complications. While a colonoscopy is not a surgical procedure, it still involves sedation and can pose some risks, especially if you have pre-existing medical conditions. Therefore, it is important to inform your doctor about any supplements or medications you are taking before the colonoscopy. It is best to follow the instructions on the label and discontinue the use of Oxyelite Pro for at least two weeks before the colonoscopy to minimize any potential risks. You should also consult your doctor before resuming the use of this supplement or any other supplement after the procedure. If you require a personalized response, kindly use the Ask A Doctor service and post a follow-up. Take care. Hope I have answered your question. Regards, Dr. Priyanka, General & Family Physician