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Can Urticaria Pigmentosa Be A Symptom Of Cancer?

My 3yr. old son has been diagnosed with Uticaria Pigmentosa. They look like moles but when scratched the area around them becomes red. My wife has read somewhere that this could in rare cases lead to cancer. I need to know if this is true and if so what preventative measures can be taken.
Mon, 4 Apr 2016
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Pediatrician,  's  Response
hi,
Welcome to this forum.
Can understand your concerns.

urticaria pigmentosa is characterized by excessive amounts of mast cells in the skin. The cause of urticaria pigmentosa is genetic.

There are some factors which can worsen the symptoms of urticaria pigmentosa like bacterial toxins,emotional stress, physical still life such as heat and friction, eyedrops containing dextran.

The diagnosis of urticaria pigmentosa is mainly based on the type of Rash which appears like bug bites. It does not lead to cancer, but mosty skin lesions which looks similar to urticaria pigmentosa can cause cancer like Melanoma, basal cell carcinoma, actinic keratosis.

To rule out possibility of Cancer, you should do a skin biopsy in which a small skin Sample is taken for microscopic examination and testing. This will help in confirming the diagnosis.

I hope this will help you.
Take care.

Regards,
Dr Deepak Patel.
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Can Urticaria Pigmentosa Be A Symptom Of Cancer?

hi, Welcome to this forum. Can understand your concerns. urticaria pigmentosa is characterized by excessive amounts of mast cells in the skin. The cause of urticaria pigmentosa is genetic. There are some factors which can worsen the symptoms of urticaria pigmentosa like bacterial toxins,emotional stress, physical still life such as heat and friction, eyedrops containing dextran. The diagnosis of urticaria pigmentosa is mainly based on the type of Rash which appears like bug bites. It does not lead to cancer, but mosty skin lesions which looks similar to urticaria pigmentosa can cause cancer like Melanoma, basal cell carcinoma, actinic keratosis. To rule out possibility of Cancer, you should do a skin biopsy in which a small skin Sample is taken for microscopic examination and testing. This will help in confirming the diagnosis. I hope this will help you. Take care. Regards, Dr Deepak Patel.