Hello and welcome to Healthcare Magic. Thanks for your query. Unexplained tiredness, fatigue and a lack of motivation can be indicative of depression. Sometimes, depression can manifest with predominantly physical or somatic symptoms, with only minimal psychological symptoms. Certain medical problems like hypothyroidism, anemia, vitamin deficiencies, etc. can also present with tiredness and fatique. I would advise you to see a doctor for a detailed evaluation in order to ascertain a likely cause for your symptoms. further treatment has to be planned according to the cause identified. You also seem to be in the midst of a stressful time - with the pressure of college, the recent passing away of your grandfather, etc. So, I would suggest that you try some destressors to try and take off the pressure. You can try relaxation techniques or talking to someone close to you to offload your burdens. Activity sheduling and planning can also help in regaining your motivation. If you feel that you are finding it difficult to cope or handle things, please don t hesitate to seek professional help. Wish you all the best. Regards, Dr. Jonas Sundarakumar Consultant Psychiatrist