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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Had Vertigo. MRI Scan Done. Have Hypothyroid. What Is This Problem?

Hi,
"Relates to Neurology"
My mother's age is 69 years old. Last week she had a vertigo, B.P. came down to 70/80 against 120/80 of normal values and she fell unconscious for which she was hospitalized for around 5 days. We were advised to got MRI done report of which shows as follows:- " Few Small ill defined foci of altered signal intensity seen in the bilateral centrum semiovale and bilateral para ventricular/subcortical fronto-parietal white matter(R>L) - suggestive of Microvascular ischaemic changes/demyelinating / gliotic foci." She does not have any disease like Sugar, Diabetes etc. except Hypothyroid. Can you please advise the intensity of problem and further advise.
Thanx,

Amit


Wed, 24 Apr 2013
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Radiologist 's  Response
Hi,

FLAIR hyperintensities in white matter are usually non-specific. The description fits that of Fazekas Grade 1 changes which are of no significance or worry, especially if you are above 40-50 years of age. However, if they worsen on follow up MRI, especially in young patients (less than 40 years), it maybe an indicator for predisposition to development of dementia early in life.

Rarely, these white matter hyperintensities can represent microvascular ischaemic diseases or demyelinating conditions but, such patients usually are markedly symptomatic for these and your mother does not seem to fit these.

Overall, these findings are probably normal for your mother's age and yopu don't need to worry about them.

Sincerely,
Vamshi
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Had Vertigo. MRI Scan Done. Have Hypothyroid. What Is This Problem?

Hi, FLAIR hyperintensities in white matter are usually non-specific. The description fits that of Fazekas Grade 1 changes which are of no significance or worry, especially if you are above 40-50 years of age. However, if they worsen on follow up MRI, especially in young patients (less than 40 years), it maybe an indicator for predisposition to development of dementia early in life. Rarely, these white matter hyperintensities can represent microvascular ischaemic diseases or demyelinating conditions but, such patients usually are markedly symptomatic for these and your mother does not seem to fit these. Overall, these findings are probably normal for your mother s age and yopu don t need to worry about them. Sincerely, Vamshi