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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Have Myelitis With TB Encephalitis. Taking Immunoglobulin And TB Medication. Further Treatment?

Dear Dr Raj, I am Dr Parija, Prof.& Head. Head & Neck Surgery at the Regional Cancer Center, at Cuttack. Orissa. I have a relation who is suffering from Myelitis since 3 months (can send u the MRI plates ) with TB Enchephalitis. On Anti. TB drugs. Have taken Immunoglobulin 20 mg/Kg at HIMHANS, Bangalore. Need to consult fr further line of treatment & an appointment. E-mail: YYYY@YYYY Mob: 0000
Fri, 13 Sep 2013
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Oncologist,  's  Response
High dose methylprednisolone is usually the initial treatment of acute transverse myelitis, (although only Class IV evidence supports this practice, which constitutes "insufficient evidence"). Similarly, "insufficient evidence" supports mitoxantrone. Plasma exchange is "possibly" useful based on 1 Class II study, and rituximab "possibly" effective based on 2 Class III studies. "Insufficient evidence" supports azathioprine, cyclophosphamide, and IVIg to alleviate symptoms or prevent future attacks.
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Have Myelitis With TB Encephalitis. Taking Immunoglobulin And TB Medication. Further Treatment?

High dose methylprednisolone is usually the initial treatment of acute transverse myelitis, (although only Class IV evidence supports this practice, which constitutes insufficient evidence ). Similarly, insufficient evidence supports mitoxantrone. Plasma exchange is possibly useful based on 1 Class II study, and rituximab possibly effective based on 2 Class III studies. Insufficient evidence supports azathioprine, cyclophosphamide, and IVIg to alleviate symptoms or prevent future attacks.