I have high cholesterol, high blood sugar, facial acne, constant hunger, my thyroid levels are off, my legs seem to swell at times, fatigue, high white blood cell count, lower back pain, heavy periods, thin hair, easy bruising, brittle nails, some facial hair, and depression. I also don't respond well to medications antibiotics don't seem to work. I am 25 and female weigh 260 and am 5'11". I have been given thyroid meds which have helped with some of the symptoms but not all. I have a suspicion that my thyroid levels being off is caused by something else I just don't know what it could be and doctors I have seen don't take me too seriously. Does this sound like it could be something else maybe more serious? Please help!!!