Hi, Ca-125 or carcinoma antigen 125 is a tumor marker produced by non mucinous epithelial tumors of ovary. Its normal levels vary from 0-35 units. Its level increases with presence of tumor and decreases or becomes absent with complete cure of ovarian tumor. A precipitous fall in CA-125 after two courses of chemotherapy is an good predictor of a complete response to chemotherapy and a good prognostic sign. It can be used for posttreatment surveillance of patients with ovarian cancer. After treatment, a delayed rise in CA-125 level is an early predictor of recurrent tumor. Keep watching for any raise in levels. For levels 20, if a second look laprotomy is done now, chances of finding a tumor is only 56%. Any further queries, happy to help again.
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Hi, Ca-125 or carcinoma antigen 125 is a tumor marker produced by non mucinous epithelial tumors of ovary. Its normal levels vary from 0-35 units. Its level increases with presence of tumor and decreases or becomes absent with complete cure of ovarian tumor. A precipitous fall in CA-125 after two courses of chemotherapy is an good predictor of a complete response to chemotherapy and a good prognostic sign. It can be used for posttreatment surveillance of patients with ovarian cancer. After treatment, a delayed rise in CA-125 level is an early predictor of recurrent tumor. Keep watching for any raise in levels. For levels 20, if a second look laprotomy is done now, chances of finding a tumor is only 56%. Any further queries, happy to help again.