Good evening sir. It is very common problem that our body stops secreting natural steroids once we r taking it from outside on a long term basis. Adrenal fatigue is common with long term use of steroids. If she is not experiencing any problems like pigmentation, low blood pressure, low blood sugar , I am not too sure how increasing the steroid dose would help. Especially if she has osteoporosis one needs to be careful. If you could provide us with some insight on adrenal fatigue symptoms, it would be more helpful. We need to be sure why we are increasing her steroid. Hope this was helpful