How To Get Rid Of Severe Knee Pain?

I am a female, 54 years, 5'3", 80 kg. Suffering from knee pain for years. The knee joint has grown large enough to need a large size knee brace. I have bood pressure, impaired glucose tolerance, elavated lipid levels, thyoroid - all controlled with medicines. Had two issue. Underwent hysterectomy in 1998. If I choose a knee replacement option now, will the trouble as well as potential infections will recur say after a decade? Will be left with any more option?