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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is Depakin 500 One Everyday An Ideal Dose?

hi my name is liridon i am 27 i had epilepsy since 7 years and i used to take aplim 500 mil now iam taking depakin 500 mil and last time i had a seizure befor 4 and half years i uesd to take one twice a day now iam taking one every day what should i do i haven consot anyone about my medication please help
Thu, 21 Apr 2016
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Neurologist 's  Response
Hi. The minimum dosage of depakin in an adult usually is above what you're taking. It depends also on your weight, lowest dose is 10mg/kg.
However if you have had no seizures in over 4 years one could consider interrupting treatment altogether. There is a risk that seizures might return, there's no guarantee on that, but since you seem to be already undermedicated you can hope for the best.
It's absolutely not something you should do on your own though, you should discuss your seizure type and history with a neurologist beforehand, it's done not abruptly but lowering the dose very gradually over the course of several weeks. An EEG would also be a helpful predictor.
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Neurologist, Surgical Dr. Bruno Mascarenhas's  Response
Hi,

I am Dr.Bruno. I have read your question and understand your concerns. Let me try to help you

The common dose 15 mg/kg per day
If you are 60 kgs, then you may need 500 mg two times a day

Hope you found the answer helpful.

If you need any clarification / have doubts / have additional questions / have follow up questions, then please do not hesitate in asking again. I will be happy to answer your questions.

Let me know if I can assist you further.

Take care.
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Is Depakin 500 One Everyday An Ideal Dose?

Hi. The minimum dosage of depakin in an adult usually is above what you re taking. It depends also on your weight, lowest dose is 10mg/kg. However if you have had no seizures in over 4 years one could consider interrupting treatment altogether. There is a risk that seizures might return, there s no guarantee on that, but since you seem to be already undermedicated you can hope for the best. It s absolutely not something you should do on your own though, you should discuss your seizure type and history with a neurologist beforehand, it s done not abruptly but lowering the dose very gradually over the course of several weeks. An EEG would also be a helpful predictor.