Is there any connection between disc bulging/herniation and hypogammaglobulinemia? I am 33yo white female with unspecified hypogammaglobulinemia and had micro-dichotomy done last year at L5-S1. I now have a bulge around the scar tissue causing symptoms once again. I am 235 # and 66.5 , yes considered obese but had lost 25# in the last few months. Now I am gaining weight back bc it is too painful to workout. I also have a history of dm2, htn, hld, bipolar, and allerges.