My daughter is now 22. She held her urine when she was young for the entire day. Urinated before she went to bed but wet the bed until she was 10. She now has hormonal problems, depression, anxiety, irregular/frequent periods, acne, migraines. Could these two things be related. She no longer holds urine or wets the bed. But, if that was caused by hormones back then, could hormones still be the problem. She is taking a birth control pill - tri-sprintec.