Hello Thank you for your query. The problem you are mentioning sounds like PCOS. It is called polycystic ovarian syndrome, wherein there are multiple cysts in the ovary and no dominant follicle or egg is produced every month for ovulation. This makes the patient prone to anovulation and difficulty in conception. you should consult an infertility specialist. Clomiphene is given to induce ovulation in patients who do not have regular periods and do not ovulate on their own. Metformin, diet, exercise, lifestyle modification and weight loss are key factors in treatment. Drilling the ovaries for PCOS ( puncturing the cysts ) is one modality but since only one ovary is affected, unless there is gross problem of PCOS, I feel no indication for it. You need to provide more details to me to comment better. take care.