Hello, Thank you for contacting us. Your wife is having bleeding in early pregnancy. Duphastone is a natural progesterone hormone preparation and is given in early pregnancy in special situations like yours to support the pregnancy and to prevent miscarriage if there is deficient progesterone production from the corpus luteum which supports the early pregnancy. But You have not mentioned anything about the Ultrasound report. I hope that it was all normal report. In that case, she can safely take the tablet. Hope to have cleared your query. Good luck.