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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Reason For Pheynetonium Level To Fluctuate?

I take Phyentonium Sodium and Levetiricem (spelling off) to control seizures. I had a brain tumor in 1981 and in 2009 I had a seizure (2 Gran Mals back to back) and then in 2013 I had a seizure but it was was a Gran Mal. Doctor said these medications are to control seizures but they are sure affecting me in a strange way. I have a balance problem with walking, vision not good, tremor movements in the hand and my speech is slurred at times. In 2009 I thought I was having a stroke. I had a tremendous headache for about two week then I all of a sudden could not speak and walk. Doctors thought it was a stroke. I had 3 MRI s and every kind of test there was. Said it probably was some scarring from 1981 surgery. Not completely sure, but started me on this medication. Just had my Lab work done to check my levels for the Pheynetonium I m taking and it is too high (23.8) reducing it by one pill. I have never had the Leveticem checked, Doctor said not necessary. My question, why do the levels fluctuate and should I be checked for another condition and a should I have Lab work for the Levetericem I take.
Wed, 15 Jun 2016
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  Anonymous's Response
's  Response
hello. Phenytoin is metabolised by liver enzymes. The level of liver enzymes are influenced by number of drugs and food items. Hence the level fluctuates
It is quite a common phenomenon in daily practice.

The purpose of doinglevels is to correct any possible toxicity, as levetiracetam has very good safety profile hence doing a its level is not advisable as no corrective actions are required even if the levels are high

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Reason For Pheynetonium Level To Fluctuate?

hello. Phenytoin is metabolised by liver enzymes. The level of liver enzymes are influenced by number of drugs and food items. Hence the level fluctuates It is quite a common phenomenon in daily practice. The purpose of doinglevels is to correct any possible toxicity, as levetiracetam has very good safety profile hence doing a its level is not advisable as no corrective actions are required even if the levels are high