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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Should Hypotrophic Kidney Be Removed To Control High BP?

Hello.
I'm male.
I'm 45 years old and I got high pressure blood since 17. I am currently taking 5 drugs to control (not at all) my high pressure blood.
In a recent Renal Angiography was discovered that I have my left kidney hypotrophic with important loss of parenchyma in the middle and lower thirds.
Analyses of plasma renin revealed that is high.

This hypotrophic kidney (left) is working by 37% and 63% right according to a renal scintigraphy.
The recommendation of my doctor(nephrology) is to get me out my hypotrophic kidney to control the high pressure blood and avoid having to take so many drugs.

What is your opinion on this?
YYYY@YYYY
Mon, 2 Jul 2018
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General & Family Physician 's  Response
Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice.

The renal angiogram and serum renin levels explain the cause of resistant hypertension(uncontrolled hypertension despite taking 3 or more antihypertensive drugs)

actually the problem in your situation is that the hypoplastic kidney receives lesser blood flow (or lesser blood flow caused hypoplastic kidney) due to which the body thinks that there is overall decrease blood pressure in body as kidney is not getting enough blood this will cause the kidney to release excessive renin which will activate angiotension and aldosterone which are the hormones in the body which cause constriction of blood vessels and retension of salt in body respectively due to which your blood pressure gets very high

removing hypoplastic kidney will breakdown this cascade and your blood pressure would stay closer to normal values

this is a classic case of renovascular hypertension.

Hope I have answered your query. Let me know if I can assist you further.
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Should Hypotrophic Kidney Be Removed To Control High BP?

Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. The renal angiogram and serum renin levels explain the cause of resistant hypertension(uncontrolled hypertension despite taking 3 or more antihypertensive drugs) actually the problem in your situation is that the hypoplastic kidney receives lesser blood flow (or lesser blood flow caused hypoplastic kidney) due to which the body thinks that there is overall decrease blood pressure in body as kidney is not getting enough blood this will cause the kidney to release excessive renin which will activate angiotension and aldosterone which are the hormones in the body which cause constriction of blood vessels and retension of salt in body respectively due to which your blood pressure gets very high removing hypoplastic kidney will breakdown this cascade and your blood pressure would stay closer to normal values this is a classic case of renovascular hypertension. Hope I have answered your query. Let me know if I can assist you further.