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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suggest Treatment For Typhoid Symptoms After Vaccination For It

my nephew, 5 years of age, was diagnosed with typhoid last May and was confined and treated with chloramphenicol, and was confined again after a month with the same diagnosis (thru typhi dot), and was treated with the same antibiotic with stronger dosage. Now after another month of being typhoid fever free (he was already given the typhoid vaccine a week after his 2nd confinement), he is showing the same symptoms again. what could be the possible cause? his mom noticed he is shedding more hair than usual too. What can we do? he weighs about 16kilos and about 3 feet tall
Thu, 26 Feb 2015
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Infectious Diseases Specialist,  's  Response
Hello. Welcome to HCM.

I am Dr Jigar(ID Specialist). I will be helping you in this matter.

If i was your treating doctor then i would have gone for following things:

1) Serological diagnosis of typhoid has limitation. Your doctor should go for Blood culture for salmonella which is the gold standard for the diagnosis and it will also confirm to which antibiotics it is sensitive and responds.

2) Chloramphenicol is one such drug which should not be used when other safe drugs are available. As it has many manageable and some severe side effects (e.g bone marrow suppression). In your case it should not be used at least in second time of illness.

3) for current illness my recommendation is do complete blood count and other blood tests after consulting a Infectious disease specialist to rule out side effects of chloramphenicol. Vaccine do not cause such illness. If typhoid is confirmed then do not go for the same drug again.

4) Give patient plenty of fluid, good nutritious diet and fruits.

I hope i have justified it. I wish rapid recovery of the patient. Do not hesitate to ask for future help.

Regards.
Dr JIgar.
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Suggest Treatment For Typhoid Symptoms After Vaccination For It

Hello. Welcome to HCM. I am Dr Jigar(ID Specialist). I will be helping you in this matter. If i was your treating doctor then i would have gone for following things: 1) Serological diagnosis of typhoid has limitation. Your doctor should go for Blood culture for salmonella which is the gold standard for the diagnosis and it will also confirm to which antibiotics it is sensitive and responds. 2) Chloramphenicol is one such drug which should not be used when other safe drugs are available. As it has many manageable and some severe side effects (e.g bone marrow suppression). In your case it should not be used at least in second time of illness. 3) for current illness my recommendation is do complete blood count and other blood tests after consulting a Infectious disease specialist to rule out side effects of chloramphenicol. Vaccine do not cause such illness. If typhoid is confirmed then do not go for the same drug again. 4) Give patient plenty of fluid, good nutritious diet and fruits. I hope i have justified it. I wish rapid recovery of the patient. Do not hesitate to ask for future help. Regards. Dr JIgar.