I am Prabhakaran.My uncle(Aged 62) has been diagnosed with acute liver cirrhosis 5months ago.He has been suffering from regular acites ever since he has been diagnosed. He also has kidney problems. He also has edema formation in his legs and scrotum. Now few days back he had black stool indicating an internal bleeding due to increased portal hypertension. He has been immediately hospitalized and treated in ICU and was given octreotide and vitamin K. Doctors say that the liver damage he sustains is irreversible. So they say that only option for us now is to live with medications and with some lifestyle modifications or transplantation(which is not affordable at the moment). absolutely its fine for us to live with medications life long but only if they work properly(.He has been prescribed to take aldactone to reduce portal pressure and some laxative and urilizer regularly). By now this is obvious that the drug given to reduce the portal pressure doesn t work,because he never had a relief from acites and edema. My question is what can we do in case of drug doesn t work? is there any better medication to treat portal hypertension? or is there any alternative treatment to reduce the portal hypertension? it seems only if we were able to reduce the portal hypertension my uncle can live with this disease without much complications. Please Help me find some better treatment for this. Thank you in advance.