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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Taking Jazz. Genetic Analysis Said Was Inclined To Having Blood Clots. Continuing Medication. What Should I Do?

Hello, Doctor. My girlfriend has been taking Jazz (Bayern) for 4 months already. She is 20. That was a recipe from the doctor,- to get rid of acne and skin problems. She's feeling alright an she got used to it. At first she had some problems with the mood, but now it's ok. I'm a little worried by the information I read on the websites about this particular product. We made a blood analysys after 1 month of taking, then after three months of taking it.
Prothrombin was 90,88, has become 85,20
MNO was 1,01, has become 1,08
We also made a genetic analysis and it said she was inclined to having blood clots (genetically) but doctors say there's no worry now, because it may reveal only after she is 35.

What should we do? Continue taking them (and how long), or stop taking them? Is this analysis enough to be sure of her health? Thank you very much. I'm looking forward to receiving the answer to my question.
Mon, 2 Sep 2013
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General & Family Physician 's  Response
Hi and thanks for the query,

I am afraid treatment in this case must not be arbitrary. It must be guided by her health status and clinical events. It might necessary to note that all people having a genetic predisposition will certainly evolve to have the disease. It is however important to have this in mind.

A continuous follow up with a hematologist is the key aspect in the management plan. Based on follow up biological parameters and results with regards to her clotting profile, specific drugs could be prescribed from time to time. Her age and clinical state do not deserve her to be put on any life long therapy as of now.

I suggest you consult a hematologist. Kind regards.

Bain LE, MD
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Note: For detailed guidance on genetic screening consult a genetics specialist
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Taking Jazz. Genetic Analysis Said Was Inclined To Having Blood Clots. Continuing Medication. What Should I Do?

Hi and thanks for the query, I am afraid treatment in this case must not be arbitrary. It must be guided by her health status and clinical events. It might necessary to note that all people having a genetic predisposition will certainly evolve to have the disease. It is however important to have this in mind. A continuous follow up with a hematologist is the key aspect in the management plan. Based on follow up biological parameters and results with regards to her clotting profile, specific drugs could be prescribed from time to time. Her age and clinical state do not deserve her to be put on any life long therapy as of now. I suggest you consult a hematologist. Kind regards. Bain LE, MD