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Oral anticoagulants(Warfarin) are the mainstay of treatment for DVT, taken lifelong if indicated. But treatment is first initiated with an injectable anticoagulant-LMWHeparin for first few weeks.
In children with thrombosis, initial anticoagulant therapy with either unfractionated heparin (UFH) or LMWH (clexane) is recommended for at least 5 to 10 days followed by VKAs (warfarin, acetrom)
Children with idiopathic thromboembolism should receive anticoagulant therapy for at least 6 months, using VKAs to achieve a target INR of 2.5 (INR range, 2.0 to 3.0) or alternatively using LMWH to maintain an anti-FXa level of 0.5 to 1.0 U/mL
Children with secondary thrombosis in whom the risk factor has resolved, anticoagulant therapy be administered for at least 3 months using VKAs to achieve a target INR of 2.5 (INR range, 2.0 to 3.0) or alternatively using LMWH to maintain an anti-FXa level of 0.5 to 1.0 U/mL
Children with recurrent idiopathic thrombosis, should receive indefinite treatment with VKAs to achieve a target INR of 2.5 (INR range, 2.0 to 3.0)
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Treatment For Deep Venous Thrombosis
Oral anticoagulants(Warfarin) are the mainstay of treatment for DVT, taken lifelong if indicated. But treatment is first initiated with an injectable anticoagulant-LMWHeparin for first few weeks.