Dear sir i can understand your concern i am very sorry about your condition i long term diabetes there is a condition called diabetic neuropathy in which the nervous system will be affected. constipation is one of the problem associated with diabetic neuropathy. there are few ways you can practice to avoid this problem. 1.your diabetes need to be under control 2.take five portions of vegetables and fruits in daily food. 3. make sure that you are taking good amount of water daily. 4.taking bulk forming agents like ispaghula husk and lactulose is also advisable. looz syrup is absolutely safe and do not contain any direct sugar which can influence your blood sugars. Hope I was able to help you. If you have any further question feel free to write me back. I will be happy to help. Take care. Best Regards. Dr Vamsi Krishna Consultant Diabetologist Apollo Hospitals