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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Are The Complications Of Higher Cholesterol While Suffering From JRA?

I have JRA for the past 17 years. to give you an idea of its severity I've had 5 total joint replacements. I was told yesterday that my cholesterol and the combination of the two could have severe complications? What are the complications? I have sustained more than 15 fractures in 2 years do to osteoporosis. I was 5ft 6inches tall 2 years ago, I'm now 5ft. I weigh 215lbs and I'm 29.
Mon, 28 Dec 2015
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Dietitian & Nutritionist,  's  Response
The increased risk the doctor is referring to is attributed to a higher prevalence of traditional cardiovascular risk factors and the role of systemic inflammation(which occurs in the juvenile arthritis process) in the acceleration of atherosclerosis.

The long-term risk of cardiovascular disease for individuals with JRA remains uncertain but it is prudent to reduce the cholesterol asap. Given the potential for longer disease duration, it is possible that cardiovascular risk in this group surpasses that observed in adult-onset inflammatory arthritis. So,the risk for heart complications increases due to the presence of the juvenile arthritis and the inflammatory condition associated with elevated lipids worsens the juvenile arthritis progression. I hope this clears things up for you. Regards, Kathryn Shattler, MS,RDN
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What Are The Complications Of Higher Cholesterol While Suffering From JRA?

The increased risk the doctor is referring to is attributed to a higher prevalence of traditional cardiovascular risk factors and the role of systemic inflammation(which occurs in the juvenile arthritis process) in the acceleration of atherosclerosis. The long-term risk of cardiovascular disease for individuals with JRA remains uncertain but it is prudent to reduce the cholesterol asap. Given the potential for longer disease duration, it is possible that cardiovascular risk in this group surpasses that observed in adult-onset inflammatory arthritis. So,the risk for heart complications increases due to the presence of the juvenile arthritis and the inflammatory condition associated with elevated lipids worsens the juvenile arthritis progression. I hope this clears things up for you. Regards, Kathryn Shattler, MS,RDN