Have complex hyperplasia without atypia, went through with one course of very low dose hormorne after first biopsy. Second biopsy had same result. Im 53.. and have not had a period for 2 years. My fsh level taken last month was 80. Dr. recommend hysterectomy or another high dose round of hormones. Don t feel comfortable with hysterectomy right now. No history of cancer in my family and no history of any female issues. Do you think I should try one more course of therapy? Filled prescription for megestrol 40mg for 3 months, but have not started them. Not sure which way to go?? What side effects will I experience with the megestrol? Would I have to have estrogen after the hysterectomy?