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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Chest Pain After Changing Medicine To Isosorbide Mono Er?

I have recently had to have a new prescription for Isosorb mono er 30 mg tablets by wes, the old one was made by tor, it has been 4 days now and I have been experiencing some chest pain which I have not had since having 4 stents placed in Nov and Dec...this is the only med that was changed and am wondering if this is even the right med..the other was white and this one is orangish with the number 3/0 printed on one side and on the other side each side of the pill has either w/w on each side..just wondering....
Tue, 25 Feb 2014
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Internal Medicine Specialist,  's  Response
Hi there,

Thanks for your query.

There should be no chest pain following change in the brand of medicine since all brands contain the same salt in the same dose.

It is therefore possible that either, the salt has degenerated; the salt is not being released regularly as it should; or, there is a manufacturing defect.

You may therefore consult your doctor and request him to prescribe the medicine of a different company or, a substitute drug, such as, Glyceryl trinitrate ER (GTN ER) is equivalent dose.

If you find my response helpful and informative, do not forget an “excellent” (5-star rating) to my answer, to ENCOURAGE ALL doctors- engaged in social service- to render sound advice to the FREE queries.

Take care

Dr. Rakesh Karanwal
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What Causes Chest Pain After Changing Medicine To Isosorbide Mono Er?

Hi there, Thanks for your query. There should be no chest pain following change in the brand of medicine since all brands contain the same salt in the same dose. It is therefore possible that either, the salt has degenerated; the salt is not being released regularly as it should; or, there is a manufacturing defect. You may therefore consult your doctor and request him to prescribe the medicine of a different company or, a substitute drug, such as, Glyceryl trinitrate ER (GTN ER) is equivalent dose. If you find my response helpful and informative, do not forget an “excellent” (5-star rating) to my answer, to ENCOURAGE ALL doctors- engaged in social service- to render sound advice to the FREE queries. Take care Dr. Rakesh Karanwal