I am a type 2 diabetic (15yrs). In November, we added AvandaMet 4/1000mg (the addition was the Metphormin) and now Onglyza 5mg. I have been having blood pressure/panic attacks at night - bp raises to 150-75/110 pulse 110-20...this when I am either in public or in bed. My regimen is 1Avandamet twice/day, Gliclazide MR 30mg x 3 in am, and Crestor in am. I have Tecta for stomach pains and Ramipril 2.5mg if either stomach or blood pressure issues arise. The only common denominator MAY be Red Wine - last night, drank 2 5oz glasses, and had an attack. I cut out caffeine this year when this all started in November/December. Been for Stress Test, heart ultrasound, thyroid test - all great. Im 39, not overweight, quit smoking 12yrs ago, poor diet, little exercise. Are one of the meds reacting with REd Wine (the only thing I drink - no beer in 10 yrs)? HELP - Ive been to hospital and they simply release when everything calms back down.