hello, Virus and any systemic infection can affect the oral tissue. Realize if your body is under stress your gums will react. Signs of Information Include bleeding and painful gums. Keep well hydrated. Proper nutrition with balanced vitamins are helpful. Make sure to include adequate amounts of vitamin B 12. Continue to practice good daily dental hygiene with gentle techniques for tender gums. Rinse your mouth with warm salt water. Take some anti-inflammatory medication such as Advil or Tylenol. Antibiotic treatment may be necessary and would require a prescription from your physician. Strep and mono are a definite possibility and can be diagnosed with further testing. See your physician for further diagnosis such as a virus, mono, flu and cold. If your oral symptoms persist, plan a visit to your dentist to evaluate your help. Early Diagnosis with her periodontal conditions will allow treatment with a good prognosis. Thank you for your inquiry. I hope you will start to feel better soon.