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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Does Dan Pcr Positive & Afb Culture Negative Suggest?

I had been diagnosed with dan pcr positive and afb culture/smear negative 2 years back. Doctor said it is normal since I have negative afb culture. But the infertility specialist say that I will have to for medication. Not sure what to do who is right??
Sat, 31 May 2014
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General Surgeon 's  Response
Hi.
Thanks for your query and an elucidate history.
IF you are from a country like India or asia, the chances of you having tuberculosis as a cause of infertility is too much. Your PCR is also positive.
You can have additional Quantiferron gold test for TB.
In addition to all this Tuberculosis is also diagnosed by clinical picture and physical findings. Loss of weight, loss of appetite, evening rise or increase in temperature or
feeling weak and frustrated by evening, loss of fat at cheeks, loss of facial luster and so many.. Also important is whether there is a history of tuberculosis in the family.

If infertility is a case an ''empirical'' treatment with anti-tubercular treatment can be started in consultation with your infertility specialist ( i hope he/she is ready for this). If the clinical improvement is positive , continue the full course .
Get liver function tests done before the treatment is started and get this repeatedly done.
All the best. You will get the positive results.
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What Does Dan Pcr Positive & Afb Culture Negative Suggest?

Hi. Thanks for your query and an elucidate history. IF you are from a country like India or asia, the chances of you having tuberculosis as a cause of infertility is too much. Your PCR is also positive. You can have additional Quantiferron gold test for TB. In addition to all this Tuberculosis is also diagnosed by clinical picture and physical findings. Loss of weight, loss of appetite, evening rise or increase in temperature or feeling weak and frustrated by evening, loss of fat at cheeks, loss of facial luster and so many.. Also important is whether there is a history of tuberculosis in the family. If infertility is a case an empirical treatment with anti-tubercular treatment can be started in consultation with your infertility specialist ( i hope he/she is ready for this). If the clinical improvement is positive , continue the full course . Get liver function tests done before the treatment is started and get this repeatedly done. All the best. You will get the positive results.