Hi, I read your problem carefully and my answer is as follows: You are telling that since 2002 you did remove thyroid due to tumor. •  Can you tell me the type of thyroid cancer (Papillar, Follicular?) •  May I know your Tg and TSH level since you operation? •  You also are telling that :THYROGLOBULIN 2.06 ng/mL range (1.60 - 59.90) Are you sure please for the range?(1.60-59.90) Because for Tg greater than .2.0 ng/ml we must to be carefully •  Did you take your dose of Thyroid hormone replacement as doctor prescribed? Did your doctor examine your neck?: •  Physical neck examination, including feeling the thyroid bed area. Typically, this is done every 3 to 6 months for the first 2 years, and at least once a year thereafter. •  Blood tests.TSH, FT3 ,FT4, Tg, Tg AB? •  Neck ultrasound. This test it is a very sensitive way to find potential disease in the neck. In these case there are three main blood tests •  Thyroglobulin (Tg): Thyroglobulin is a protein produced by thyroid cells (both normal and cancerous cells). I am telling that after your surgery and RAI, it may take months or years for the Tg number to come down to zero or undetectable. Depending on the level of Tg in your blood, your doctor may want to monitor you more closely with other tests or scans and/or prescribe additional treatment. Thyroglobulin testing can be more accurate when your TSH level is elevated. •   TSHAnti-thyroglobulin anti-bodies (TgAb): My advise is to check thyroid hormone level, TSH, Ft3, Ft4, Tg, TgAB. Consult with your doctor and endocrinologist. In my opinion you must to do an ultarsound and scan. Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Klodiana Poshi