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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Is Exfoliative Erythroderma?

My father has been diagnosed recently with exfoliative erythroderma, they put him on an immune suppressant i'm not quite understanding the reasoning for this...also, treatment options seem to be far and few between do you have any knowledge on this particular disease/disorder...? He is 47 years of age and has been suffering from this for around 4 years now. He is so cold all the time. I just want to find him help

Wed, 27 Aug 2014
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Addiction Medicine Specialist,  's  Response
exfoliative erythroderma is an immune reaction in which the skin gets red and falls off. The skin falling off acts as a severe burn and is a serious condition and a reason to immunosuppress. Etiologies are often unknown, but fall into two groups: one is purely an immune reaction and can be to a known thing someone is allergic to (drug reaction. skin exposure). In these cases, with removal of the allergen, the condition gets better. Mostly the allergen isn't so clear or its autoimmune (psoriasis). The other group are cancers (generally blood cell cancers) that invade the skin and cause inflammation. Skin biopsy would be the first stage. Then removal of allergen, or treating the cancer; mostly, giving immunosuppressants is all that can be done.
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What Is Exfoliative Erythroderma?

exfoliative erythroderma is an immune reaction in which the skin gets red and falls off. The skin falling off acts as a severe burn and is a serious condition and a reason to immunosuppress. Etiologies are often unknown, but fall into two groups: one is purely an immune reaction and can be to a known thing someone is allergic to (drug reaction. skin exposure). In these cases, with removal of the allergen, the condition gets better. Mostly the allergen isn t so clear or its autoimmune (psoriasis). The other group are cancers (generally blood cell cancers) that invade the skin and cause inflammation. Skin biopsy would be the first stage. Then removal of allergen, or treating the cancer; mostly, giving immunosuppressants is all that can be done.