Hello and thank you for using HCM.
I carefully read your question and I understand your concern.
I will try to give you my opinion about this.
When we treat a hypertensive patient our goal is to keep the blood pressure below 140/90 mmHg. If it exceeds this mean values than we should intervene to correct the therapy.
The most important thing is to menage the problems or the reasons that might have cause this blood pressure altering.
As you mention, your husband has been on antibiotics, so he might have an active infection. Sometimes this infection alter the hole
metabolism and blood pressure. But the most important thing is to evaluate the renal function.
Hypertension is strongly related with alteration of renal function. So the most important thing is to menage the renal function and to correct the
blood pressure medication according to renal function.
You must know that there are some anti-hypertenive drugs that should be caution if it is a renal impairment.
Normally if renal function is improved this is better in controlling blood pressure values, so thinks should be improved.
But even though, we can menage thinks with adding or correcting blood pressure medicines.
Excessive blood values might be the cause of
shortness of breath.
If I was your treating doctor i will ask for a fool blood analyze to check the renal
creatinine, a cardiac echo to check heart function and a holter blood pressure monitoring to evaluate values through day and night.
Only after this examinations we can better judge how to correct the drugs.
Hope I was helpful.Wish your husband good health.
Best regards.