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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Why Morphine Sulfate For Back Pain Did Not Show Up In Saliva Test?

I have been on Morphine Sulfate ER 60 mg BID for back pain and my last 3 drug screens have not detected in my saliva. I have been taking my medication as prescribed. I am about 5 8 and about 320 lbs. Can you give me any explanation as to why it wouldn t show up in the saliva test. I just went to my PCP yesterday and he did order me a blood test to check. I am awaiting those results. Thank you, Lynn Schututer
Tue, 29 Apr 2014
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Dentist, Oral and Maxillofacial Surgery,  's  Response
hello thanks for consultation with hcm..a cut off concentration of 40ng/ml for immunoassay screening for Opiates in saliva. The saliva Test will give a positive result if morphine is present at or above this concentration in human saliva. A more specific alternate chemical method must be used in order to obtain a confirmed analytical result. Gas chromatography/mass spectrophotometry (GC/MS) is the preferred confirmatory method.Hence ur treating physician has suggested a blood test..hope it helps,,tc
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Why Morphine Sulfate For Back Pain Did Not Show Up In Saliva Test?

hello thanks for consultation with hcm..a cut off concentration of 40ng/ml for immunoassay screening for Opiates in saliva. The saliva Test will give a positive result if morphine is present at or above this concentration in human saliva. A more specific alternate chemical method must be used in order to obtain a confirmed analytical result. Gas chromatography/mass spectrophotometry (GC/MS) is the preferred confirmatory method.Hence ur treating physician has suggested a blood test..hope it helps,,tc