Hi, I had my first depo provera shot for suspected endometriosis on sept 19, and started to feel very I ll on 1 dec. Extreme fatigue, nausea, pain, headaches and fuzzy head, crying all the time. I went to the doctor and they didn t say that it could be due to depo. I started to feel a bit better on 5 Jan, but on 12 Jan they advised me to have the next injection so I did. 3 days after the injection all my fatigue and depressions symptoms are back, plus I have itchy spots on my scalp, and my hair is falling out. My progesterone levels taken on 14 dec are 0.7 which I know is very low. If I was told how this drug would make me feel I would not have touched it. Do you think that my symptoms Are due to adrenal fatigue/low progesterone because of the depo? If so, how can I get the drug out of my body quicker, and will my cortisol and progesterone levels rise again once it is out of my body, or will I need to boost them. Thanks Ella