malabsorption, excessive loss, or a combination of these factors. Most of the symptoms of the disease are reversible and if treated promptly and earlier they resolve without leaving any sequelae. Infants typically present with periorificial and acral dermatitis, diarrhea, behavioral changes and neurologic disturbances. Older children may show features of failure to thrive, alopecia, anorexia and nail dystrophies, even frequent infections are common. If the condition is left untreated then the patient may die in first few years and may show growth retardation, dermatitis, alopecia and repeated superficial infections. All the symptoms are reversible with the treatment and the patients respond well. The disease shows no sexual preponderance; both the sexes are equally affected. Symptoms of the disease appear typically when the infant is weaned from breastfeeding. inadequate intake,
Diagnosis is mainly based on the clinical symptoms and the presentation along with the typical age of presentation. Blood tests are done to establish the diagnosis of low zinc values and to look for any concurrent infections or disorders.