
Suffer Bad Depression And Methadone Program. Take Zanax For Anxiety. Feeling Sleepy. Remedy?

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Detailed Answer:
Hello
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You are 37 yrs old and are suffering from severe depression. You have taken many anti-depressant drugs but none worked. You started using heroin and then started with methadone program. You are taking Xanax for anxiety. Currently you are not able to stop methadone because of fear of withdrawal. Xanax is not working in anxiety.
Currently you are suffering from severe tiredness. You are not finding pleasure in any thing. You are not able to feel something. You are getting no motivation. Most of the symptoms you have mentioned are of severe depression only. There is urgent need for consultation of a psychiatrist. Although the common anti-depressant didn't work still many drugs are useful in poor response depression. SSRI drugs like sertaline, fluoxetine with some other drug like bupropion, mirtazepine can control such symptoms. Most of symptoms you are having are related to low motivation and apathy and amisulpiride is good drug for such negative symptoms.
As depression failed to response to drugs so there may be some possible underlying cause behind poor response. Methadone or opioids worsen the depressive symptoms. Low thyroid hormones, low Vitamin B 12 levels are common features in resistant depression. Impaired glucose levels and cortisol levels are also common. I would advise you to go for tests like Thyroid hormone levels, vitamin B12 levels, Serum cortisol etc, and if any value come abnormal consult your psychiatrist for replacement medicines.
Supplements containing Omega 3 Fatty acids, Methylcobalamin help in speedy recovery in depressive symptoms. So I would advise you to consult your psychiatrist for quick relief.
To prevent withdrawal from methadone best thing to do is gradually taper the drug over 8-10 weeks. To prevent anxiety and withdrawal symptoms medicines like clonidine are used.
Apart from medicines, psychological treatment like Cognitive Therapy is very useful in depression cases.
Hope I cleared your doubt, if you have more questions you can ask again.
Thanks


Hello again
Detailed Answer:
SSRI drugs are most commonly used anti-depressants and I think you have been prescribed with these drugs also. Escitalopram, Sertaline, Paroxetine etc are SSRIs. Desvenlafexine is SNRI drug and it is a good anti-depressant. But you have mentioned that you failed to respond to common anti-depressants so in such case some additive drug is added to therapy for relief. Thyroid hormones, lithium, lamotrigine etc drugs are commonly used to augment the effects of anti-depressants.
I have already mentioned the need for supplements. Methylcobalamine and Vitamin B12 are very useful supplements in depression.
The behavior you have shown may be normal adolescent problem and it is commonly seen in a lot of youngsters but some times it may become root of depression in future, proper psychological evaluation is needed to ascertain this as cause of depression.
If you are still not sure about your depressive symptoms many stronger drugs like Mirtazepine, Trazodon with amisulpiride can be used, you can discuss with your psychiatrist for that.
Please believe in medicines, most of medicines took about 6-8 weeks to show their effect.
Hope this helps you, if you have more questions you can ask again.
Thanks

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