Hello friend, Thank you for posting your query through Healthcare magic. I feel sympathy because of your insistence to use the drug in spite of understanding that it is harmful. Accutane is a drug of conventional medicine s acne management. Still I have understood that it has got very serious side effects like hearing and vision problems, damage to liver and pancreas etc as long term side effects and dry lips, drowsiness, cracking and peeling of skin, itching, back pain, rashes etc as short term side effects. It is having seizures, loss of appetite, fevers, blisters, red skin , numbness etc as very serious short term side effects also. You also experienced a cystic flare after using it. Still you use it because you are given to understand that for a disease on your skin, you have to use an external remedy to manage it. Also you are ignorant that there is another safe, simple and curative method for treating this disease. Therefore you go on using it and go ahead with readiness to face its side effects. I am a Homoeopath and that is why I share these different thoughts with you. You may please try to understand that any chronic disease and so acne also is a constitutional problem and you need constitutional internal remedies to cure your tendency to develop acne of any type. There are about 150 Homoeopathic remedies to cure acne of various types. Out of them which remedy will suit your constitution and cure you is decided by an expert Homoeopathic physician and so I advise you to approach one such expert at the earliest. Or you can also get back to me with more details about you for curative treatment. You can use the premium follow up question facility of Healthcare magic for that. With Best Wishes, Dr C. J. Varghese, Homoeopath, drcjvarghese@gmail.com.