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Does Vagifem Causes The Clot To Grow?
Hi I am 51 eigh 57kg and are generally healthy and active. Had total hysterectomy 7 Oct 2013 and developed femoral dvt 2 weeks later. Am on warfarin. Leg still swells a lot as clot is still present. I went to menopause specialist due to anxiety and hot flushes and pain during intercourse. He prescribed vagifem 25mg and assured me the dosage is too low to interfere with blood as I am on warfarin anyway. I am very worried that using it will cause the clot to grow? He also prescribed venlor 37.5mg for hot flushes and assured me I will not gain weight? Please tell me if this is ok or should I worry?
Mon, 10 Mar 2014
Hello
If you already have a clot and are on Warfarin, it is not worth taking the risk of any estorgen derivatives no matter what the preparation or amounts. and plus your are anxious about taking it. I suggest use simple K Y gelly for lubrication during sex. If you are allowed to be mobile do some physical activity all the time, it will keep your mind active and less depressed.
Take care
If you already have a clot and are on Warfarin, it is not worth taking the risk of any estorgen derivatives no matter what the preparation or amounts. and plus your are anxious about taking it. I suggest use simple K Y gelly for lubrication during sex. If you are allowed to be mobile do some physical activity all the time, it will keep your mind active and less depressed.
Take care
I find this answer helpful
**
1. vagifem [estradiol] tablets works by replacing natural estrogens in a woman who can no longer produce enough estrogen, [as total hysterectomy] is there and to treat menopausal changes in and around the vagina.
2. vagifem has dual effect with warfarin:
i. it may increase the actions and the risk of side effects of warfarin [bleeding problems]
ii. it may decrease the effectiveness of warfarin [ may increase the risk of blood clots.]
PS. as suggested by history : leg still swells, thus check with your Primary care doctor before you start, stop, or change the dose of any medicine.
3. also one has to exclude the possibilities of abnormal calcium levels in the blood, asthma, cancer, certain blood disorder (porphyria), lipid problems, depression, diabetes, excessive weight gain, gallbladder disease, heart disease or other heart problems, high blood pressure, kidney or liver disease, low thyroid hormone levels, lupus, migraine headaches, pancreas disease, seizures, or yellowing of the skin or eyes..... since these medical conditions may interact with Estrace.
PS. Lab tests, including physical examinations and blood pressure, may be performed while you use vagifem. You should have breast and pelvic exams, and a Pap test at least once a year. You should also have periodic mammograms and be sure to keep all doctor and lab appointments.
4. venlor [venlaxafine] is an anti depressant used to treat depression and other mood disorders, including social anxiety disorder, panic disorder, and generalised anxiety disorder, and since it causes loss of appetite thus weight gain is not there but since it causes vasodilation thus hot flashes can be bothersome [which you are already experiencing]
PS. Venlor when taken with warfarin may affect affects blood clotting as these may increase risk of bleeding.
1. vagifem [estradiol] tablets works by replacing natural estrogens in a woman who can no longer produce enough estrogen, [as total hysterectomy] is there and to treat menopausal changes in and around the vagina.
2. vagifem has dual effect with warfarin:
i. it may increase the actions and the risk of side effects of warfarin [bleeding problems]
ii. it may decrease the effectiveness of warfarin [ may increase the risk of blood clots.]
PS. as suggested by history : leg still swells, thus check with your Primary care doctor before you start, stop, or change the dose of any medicine.
3. also one has to exclude the possibilities of abnormal calcium levels in the blood, asthma, cancer, certain blood disorder (porphyria), lipid problems, depression, diabetes, excessive weight gain, gallbladder disease, heart disease or other heart problems, high blood pressure, kidney or liver disease, low thyroid hormone levels, lupus, migraine headaches, pancreas disease, seizures, or yellowing of the skin or eyes..... since these medical conditions may interact with Estrace.
PS. Lab tests, including physical examinations and blood pressure, may be performed while you use vagifem. You should have breast and pelvic exams, and a Pap test at least once a year. You should also have periodic mammograms and be sure to keep all doctor and lab appointments.
4. venlor [venlaxafine] is an anti depressant used to treat depression and other mood disorders, including social anxiety disorder, panic disorder, and generalised anxiety disorder, and since it causes loss of appetite thus weight gain is not there but since it causes vasodilation thus hot flashes can be bothersome [which you are already experiencing]
PS. Venlor when taken with warfarin may affect affects blood clotting as these may increase risk of bleeding.
I find this answer helpful
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