Hi,I am Dr. Robert Galamaga (Hematologist). I will be looking into your question and guiding you through the process. Please write your question below.
Have Multiple Myeloma. Prescribed Pomalyst. Will Drop In Blood Levels?
I have multiple myeloma and was prescribed pomalyst(celgene) 4mg with dex. I'm 5'5" weigh 95 lbs. and am 75 yrs old. What are the weight guidelines for this drug? Can't find this information in any of Celgene's patient studies. Since this drug can cause a significant drop in various blood levels, this is a concern. I have been on several chemo drugs. My oncologist doesn't have the answer.
Hello, POMALYST is indicated for patients with multiple myeloma who have received at least two prior therapies and have demonstrated disease progression on or within 60 days of completion of the last therapy.
The recommended starting dose of POMALYST is 4 mg once daily orally on Days 1-21 of repeated 28-day cycles until disease progression. POMALYST may be given in combination with dexamethasone. The side effects of this drug are NEUTROPENIA and THROBOCYTOPENIA.
If the toxicity with the drug is seen,then the therapy is started with dose of 3 mg ( one mg less than starting dose )
To initiate a new cycle of POMALYST, the neutrophil count must be at least 500 per mcL, the platelet count must be at least 50,000 per mcL. If toxicities occur after dose reductions to 1 mg, then discontinue POMALYST. Discuss about this with your doctor. I hope it helps Thanks
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Have Multiple Myeloma. Prescribed Pomalyst. Will Drop In Blood Levels?
Hello, POMALYST is indicated for patients with multiple myeloma who have received at least two prior therapies and have demonstrated disease progression on or within 60 days of completion of the last therapy. The recommended starting dose of POMALYST is 4 mg once daily orally on Days 1-21 of repeated 28-day cycles until disease progression. POMALYST may be given in combination with dexamethasone. The side effects of this drug are NEUTROPENIA and THROBOCYTOPENIA. If the toxicity with the drug is seen,then the therapy is started with dose of 3 mg ( one mg less than starting dose ) To initiate a new cycle of POMALYST, the neutrophil count must be at least 500 per mcL, the platelet count must be at least 50,000 per mcL. If toxicities occur after dose reductions to 1 mg, then discontinue POMALYST. Discuss about this with your doctor. I hope it helps Thanks