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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is Duphaston And Cyclogest Switching Safe During A Pregnancy?

Hi im 9 and half weeks pregnant... I was given cyclogest from week 5 as I saw brown bleeding and brown mucous. Despite the fact that bleeding supsided a little I still saw bleeding at least 2ce a week. The doctor suggested I have duphaston instead 3 times a day. After 5 days of havinh the pills the bleeding increased. In the last two days I see some brown bleeding and spottong each time I go to the bathroom. The doctor suggested I should take cyclogest again this time one in the morning and one in the evening 400mg each. Do u think its safe to switch each time medications im really worried about this bleeding. 2 days ago I had an ultrasound and it looked ok heartbeat and all. But im still very worried of what to do.i had a hidtory of one miscarraige at 8 weeks. It was missed.
Wed, 2 Mar 2016
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OBGYN 's  Response
Hi there,
Welcome to HCM,

Both Duphaston and Cyclogest are same hormone progesterone but the method of intake is different.

They are given to support pregnancy, but exactly how useful they are in preventing miscarriage is yet to be proven.

The fact that the ultrasound is normal and fetal heart rate is good implies that things are ok. Once the fetal heart beat appears there is very little chance of you having a miscarriage.

I understand with your previous history of miscarriage you must be very anxious but the stress and anxiety can make matters worse for you.

The bleeding should subside by around 12 weeks. The oral form Duphaston is easier to take and less cumbersome. Threatened miscarriage is common in early pregnancy and only supportive care with rest is advised. You could continue either of the progesterone, whichever you are more comfortable with.

Get a repeat scan after 10 days to check for fetal well being.
Do not worry.

Hope this helps.
Regards.
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Is Duphaston And Cyclogest Switching Safe During A Pregnancy?

Hi there, Welcome to HCM, Both Duphaston and Cyclogest are same hormone progesterone but the method of intake is different. They are given to support pregnancy, but exactly how useful they are in preventing miscarriage is yet to be proven. The fact that the ultrasound is normal and fetal heart rate is good implies that things are ok. Once the fetal heart beat appears there is very little chance of you having a miscarriage. I understand with your previous history of miscarriage you must be very anxious but the stress and anxiety can make matters worse for you. The bleeding should subside by around 12 weeks. The oral form Duphaston is easier to take and less cumbersome. Threatened miscarriage is common in early pregnancy and only supportive care with rest is advised. You could continue either of the progesterone, whichever you are more comfortable with. Get a repeat scan after 10 days to check for fetal well being. Do not worry. Hope this helps. Regards.