Hello and welcome to healthcaremagic I can understand your concern and frustration regarding the chronicity of psoriasis. Psoriasis has a chronic course, the course being fluctuated by remissions and relapses, however there is no permanent cure for psoriasis. Psoriasis is characterized by the presence of well defined, thick scaly plaques mainly involving the scalp, and extensor surfaces like hands, feet/soles, elbow, knee, lower back etc. Specific topical treatment options for psoriatic plaques affecting the soles and legs includes potent topical steroid,either plain or in combination with salicylic acid. Topical Vitamin D analogues like calcipotriol, calcipotriene etc are also effective for localized plaque psoriasis affecting the soles and legs. Oral agents includes Immunosuppressives like methotrexate, Oral retinoids(Acitretin). Although they are mainly indicated for widespread disese involment, however, they can be used for limited yet disabling disease involving the palms and soles. Biologics like Infliximab, Adalimumab, Etanercept are newer remedies and includes monoclonal antibodies, interleukins, interferons and colony stimulating factors etc. Treatment depends on the severity of the disease. While limited disease can be managed with just topicals, widespread or extensive disease may require hospitalization. I would suggest that you seek an appointment with a dermatologist in your vicinity, who would be able to assess the severity of your disease and advice accordingly. Hope this helps Regards