Hi, thank you for providing the brief history of your husband. As he is suffering from vascular dementia, i will advice to undergo a clinical neurological examination. May be an MRI will be required to understand the brain areas better. As medicine helps on a symptomatic relief and too much medication will not be good for the general health of the kidneys. Prednisone on a longer run also has some negative effects and the GP may not prescribe anymore. Also, in my clinical practice most patients with neurological illness, responds well to physical therapy along with medication. As with physical therapy exercises the metabolism is improved and so the vascular blood flow to the brain by improved cardio respiratory endurance. Regards Jay Indravadan Patel